P104 Patient perception of NIV success doesn’t correlate with QOL.

Abstract Background It is unknown if success in NIV translates to better Quality of Life (QOL) for patient. Objective To evaluate the correlation between patients’ perceptions of the effectiveness of NIV therapy and their QOL as measured by the Severe Respiratory Insufficiency (SRI) questionnaire. Methods Patients on long term NIV were asked to rate the effectiveness of their NIV therapy on a Likert scale and complete the SRI, a validated QOL questionnaire for patients on home ventilation scoring patients across 7 domains on a scale of 0 to 100. Results 37 patients (20 males and 17 females, median age 68 years old) completed both NIV effectiveness scale and SRI. They were on NIV therapy for a mean of 17 months. Primary indications for NIV were obesity-hyperventilation syndrome (27%), chronic heart failure (21.6%) and obstructive airway disease (24.3%). Patients generally rated the NIV therapy to be effective, scoring effectiveness as 7.75 out of 10, ranging from 2 to 10 with SD 1.96. Mean SRI was 57, suggesting moderately impaired QOL. There was no significant correlation between SRI and the NIV efficacy score (r = -0.05). Patients scored most poorly in domains measuring physical functioning (SRI-PF 43) and psychological well-being (SRI-WB 52). Conclusion Our data showed that even when patients perceive that their NIV is effective, this may not translate into better QOL scores. More attention needs to be paid to factors that impact patient QOL.