Cytokine and IRF5 Gene Polymorphisms Associated With Susceptibility and Organ Damage in Systemic Lupus Erythematosus
Our findings support a role for IRF5 and cytokine gene polymorphisms in the genetic predisposition to SLE and its clinical manifestations. These polymorphisms may serve as potential biomarkers for disease risk stratification and personalized patient management, particularly in underrepresented populations such as North Africans.
Authors
- Lylia Meriem Berkani
- Sihem Oulakrouz
- Brahim Belaid (ORCID: https://orcid.org/0000-0001-7618-4051)
- Messaoud Saidani
- Réda Djidjik (ORCID: https://orcid.org/0000-0003-0820-692X)
- S. Ayoub
- Ines Allam
- Yousra Hassinet
- Chahrazad Zeghichi
Institutions
- University of Algiers Benyoucef Benkhedda (DZ)
- University of Algiers 3 (DZ)
Publication Details
- Journal
- International Journal of Immunogenetics
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1111/iji.70016
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00