Steroid‐Induced Takotsubo Cardiomyopathy in a Patient With Immune Thrombocytopenic Purpura
ABSTRACT This case report highlights a temporal relationship between dexamethasone administration and the onset of Takotsubo cardiomyopathy, underscoring the importance of recognizing pharmacologic agents as potential non‐traditional triggers, particularly in patients with underlying cardiovascular disease and no identifiable emotional or physical stressors. Diagnosis favored a dexamethasone‐triggered Takotsubo phenotype based on non‐obstructive coronaries, regional wall‐motion abnormalities extending beyond a single arterial territory, absence of alternate stressors, and biologic plausibility of steroid‐mediated catecholaminergic upregulation.
Authors
- Abdalhakim R. M. Shubietah (ORCID: https://orcid.org/0000-0002-8300-0262)
- Muath Baniowda (ORCID: https://orcid.org/0000-0002-0457-738X)
- Mohammad Alqadi (ORCID: https://orcid.org/0000-0003-2055-2681)
- Imad Hariri
- Qutaiba Qafisheh (ORCID: https://orcid.org/0000-0002-2128-4028)
- Mohanad Qwaider (ORCID: https://orcid.org/0009-0002-2150-5772)
- Roaa Aljunaidi (ORCID: https://orcid.org/0000-0003-2506-9592)
- Wael Hashem (ORCID: https://orcid.org/0009-0009-5346-9973)
- Mohammed AbuBaha (ORCID: https://orcid.org/0009-0000-0873-8374)
Institutions
- An-Najah National University (PS)
- ProMedica Toledo Hospital (US)
- Palestine Polytechnic University (PS)
- ProMedica Russell J. Ebeid Children's Hospital (US)
- Advocate Illinois Masonic Medical Center (US)
- University of Missouri–Kansas City (US)
- University of Toledo (US)
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/ccr3.71047
- Primary Topic
- Takotsubo Cardiomyopathy and Associated Phenomena
- Type
- article
- Field-Weighted Citation Impact
- 0.00