Lung epithelial injury impairs early host immune responses to Mycobacterium tuberculosis

These findings indicate that pulmonary epithelial integrity may influence early host immune responses to Mycobacterium tuberculosis and provide a transcriptomic framework for exploring epithelial-immune crosstalk as a potential therapeutic target.

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Publication Details

Journal
Inflammation Research
Published
2025-10-03
DOI
https://doi.org/10.1007/s00011-025-02106-4
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Lung epithelial injury impairs early host immune responses to Mycobacterium tuberculosis

Junping Wu, Guiying Xu, Zhi‐Zhu He, Yu Li et al.
Inflammation Research
Tuberculosis Research and Epidemiology
article

Lung epithelial injury impairs early host immune responses to Mycobacterium tuberculosis

Junping Wu, Guiying Xu, Zhi‐Zhu He, Yu Li, Xue Li, Youwei Wang, Miao Xuan, Qi Wu, Huaiyong Chen
article en

Abstract

These findings indicate that pulmonary epithelial integrity may influence early host immune responses to Mycobacterium tuberculosis and provide a transcriptomic framework for exploring epithelial-immune crosstalk as a potential therapeutic target.

Inflammation ResearchVol. 74(1)
Tianjin University (CN), Tianjin haihe hospital (CN), Tianjin Medical University (CN)
Openalex Percentile: Top 68%
Tuberculosis Research and Epidemiology
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