Network-based mapping and neurotransmitter architecture of brain gray matter correlates of extraversion
Despite regional heterogeneity in prior VBM studies, structural GM correlates of extraversion consistently map onto the DMN and FPN. This network-based approach reconciles previous inconsistencies and highlights the importance of these large-scale networks as a plausible functional substrate underlying structural variations associated with extraversion. These findings advance a systems-level understanding of the neural basis of this core personality dimension and suggest a distinct neurochemical architecture within these networks.
Authors
- Feng Zhang (ORCID: https://orcid.org/0000-0002-7845-7970)
- PingLei Pan (ORCID: https://orcid.org/0000-0002-9288-6384)
- Shu Wang (ORCID: https://orcid.org/0000-0002-5914-0804)
- Xiaoyi Liu (ORCID: https://orcid.org/0009-0006-5862-2031)
- Zhenyu Dai (ORCID: https://orcid.org/0000-0003-1856-5061)
- Hai-Hua Sun
- Hucheng Yang
- Siyu Gu
Institutions
- Yancheng Third People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Systems Neuroscience
- Published
- 2025-10-03
- DOI
- https://doi.org/10.3389/fnsys.2025.1640639
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Jiangsu Commission of Health
- Anhui Medical University
- Nantong University
- Bijzonder Onderzoeksfonds UGent