Sodium–Glucose Cotransporter 2 Inhibitors and Lower Risk of Depression in Population with Type 2 Diabetes Mellitus: A Population-Based Active Comparator, New-User Design
SGLT2i use was associated with a reduced risk of depression among individuals with type 2 diabetes mellitus. These findings suggest potential neuropsychiatric benefits of SGLT2i and support further investigation into their broader therapeutic implications.
Authors
- Ying‐Chih Huang (ORCID: https://orcid.org/0000-0002-9559-9428)
- Man-Ling Kao
- Sheng-Yin To (ORCID: https://orcid.org/0009-0007-5996-2879)
- Wen-Chi Huang (ORCID: https://orcid.org/0000-0001-5556-1460)
- Li‐Ting Kao (ORCID: https://orcid.org/0000-0003-0692-7408)
- Yuan-Liang Wen
- Chun‐Cheng Liao (ORCID: https://orcid.org/0000-0002-7508-6297)
- Huiwen Yang (ORCID: https://orcid.org/0009-0003-5768-8424)
Institutions
- Tri-Service General Hospital (TW)
- Taoyuan Armed Forces General Hospital (TW)
- Taipei Medical University-Shuang Ho Hospital (TW)
- Taichung Armed Forces General Hospital (TW)
- Taipei Medical University (TW)
- National Defense Medical Center (TW)
Publication Details
- Journal
- Clinical Epidemiology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2147/clep.s536542
- Citations
- 1
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- Taipei Medical University
- Tri-Service General Hospital
- Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare
- Medical Affairs Bureau