Sex-specific gene expression and weighted co-expression network analysis suggest distinct sex-specific molecular signatures in acutely suicidal MDD-patients without somatic comorbidities
Collectively, these findings underscore the critical importance of sex-specific molecular research in acutely suicidal MDD patients and may inform the development of more targeted therapeutic approaches.
Authors
- David Engblom (ORCID: https://orcid.org/0000-0001-6501-9077)
- Sílvia Castany (ORCID: https://orcid.org/0000-0002-9530-2647)
- Christian Montag (ORCID: https://orcid.org/0000-0001-8112-0837)
- Heidrun Haas
- Michael Fritz (ORCID: https://orcid.org/0000-0003-1336-5116)
- Manuela Dudeck (ORCID: https://orcid.org/0009-0008-0078-5078)
- Judith Streb (ORCID: https://orcid.org/0000-0003-0751-5835)
- Karlheinz Holzmann
Institutions
- Linköping University (SE)
- Universität Ulm (DE)
- University of Macau (MO)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-10-03
- DOI
- https://doi.org/10.3389/fgene.2025.1653768
- Citations
- 1
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.58