Exploring the antioxidant potential of prolactin

Hyperprolactinemia elevated total antioxidant and thiol levels while suppressing total oxidants, oxidative stress, and disulfide/thiol ratios. These findings indicate that prolactin plays a pivotal role in maintaining thiol-disulfide homeostasis and oxidative balance, functioning as a crucial endogenous antioxidant hormone. Moreover, the elevated prolactin levels during gestation and lactation may reflect its essential contribution to maternal-infant antioxidant defense, thereby supporting optimal fetal development.