Wenyang Zhenshuai Granules inhibits cardiomyocyte apoptosis in chronic heart failure by regulating p38 MAPK signaling pathway through exosomal miR-155

WZG inhibits p38 MAPK protein phosphorylation via exosomal miR-155, thereby exerting anti-apoptotic effects on cardiomyocytes in CHF.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-10-03
DOI
https://doi.org/10.3389/fphar.2025.1538091
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Wenyang Zhenshuai Granules inhibits cardiomyocyte apoptosis in chronic heart failure by regulating p38 MAPK signaling pathway through exosomal miR-155

Yanping Tang, Huzhi Cai, Fang Zhou, Liqi Peng et al.
Frontiers in Pharmacology
Extracellular vesicles in disease
article

Wenyang Zhenshuai Granules inhibits cardiomyocyte apoptosis in chronic heart failure by regulating p38 MAPK signaling pathway through exosomal miR-155

Yanping Tang, Huzhi Cai, Fang Zhou, Liqi Peng, Q. Chen, Xinyu Chen
article en

Abstract

WZG inhibits p38 MAPK protein phosphorylation via exosomal miR-155, thereby exerting anti-apoptotic effects on cardiomyocytes in CHF.

Frontiers in PharmacologyVol. 16
Hunan University of Traditional Chinese Medicine (CN), First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 76%
Extracellular vesicles in disease
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