Electroacupuncture therapy and bone cancer pain relief: experimental study on analgesic mechanisms in rats
Electroacupuncture significantly reduced the pain threshold in rats with bone cancer pain. This effect is likely due to the down-regulation of GSK-3 activity, inhibition of astrocyte activation, and reduction in inflammatory responses.
Authors
- Yongzhong Wu (ORCID: https://orcid.org/0000-0001-8367-3347)
- Dongqin Xia (ORCID: https://orcid.org/0000-0001-6677-1105)
- Yànhuá Lǐ (ORCID: https://orcid.org/0000-0002-2141-5139)
- Caizhi Xiao (ORCID: https://orcid.org/0000-0003-0503-7964)
- Jie Cao (ORCID: https://orcid.org/0000-0001-6058-4608)
- Fangfei Li (ORCID: https://orcid.org/0000-0002-9108-809X)
Institutions
- Chongqing University (CN)
- Chongqing Cancer Hospital (CN)
Publication Details
- Journal
- Frontiers in Pain Research
- Published
- 2025-10-03
- DOI
- https://doi.org/10.3389/fpain.2025.1597472
- Primary Topic
- Acupuncture Treatment Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00