The Effect of Halp Score on the Development of Pharyngocutaneous Fistula After Laryngectomy

Aim: Laryngeal cancers are prominent among head and neck cancers, and laryngectomy is commonly performed in advanced cases. Pharyngocutaneous fistula (PCF), a postoperative complication, negatively impacts quality of life, prolongs hospitalization, and delays treatment. The Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) score, calculated from hemoglobin, albumin, lymphocyte, and platelet levels, reflects immune and nutritional status. Material and Methods: This retrospective study included 76 patients who underwent surgery for laryngeal cancer between January 2012 and June 2024. Patients were grouped based on partial or total laryngectomy, and HALP scores were compared with the incidence of fistula. Results: In the total laryngectomy group, the mean HALP score was 33.42±17.17 for patients without fistula and 42.79±30.00 for those with fistula. No statistically significant difference was found between the two groups (p>0.05). Conclusion: No significant relationship was found between HALP score and PCF development. However, since hemoglobin and albumin may be risk factors, larger, multicenter prospective studies are needed for a more comprehensive evaluation