Interplay of Serum Potassium and Kidney Function with Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction: Findings from FINEARTS-HF
No significant heterogeneity was found on the effect of finerenone to reduce primary outcome events. Still, adverse events and treatment discontinuation were more frequent among patients with low eGFR and/or high K<sup>+</sup>, suggesting. that such patients may require tailored strategies to mitigate adverse events and avoid treatment discontinuation.
Authors
- Brian Lee Claggett (ORCID: https://orcid.org/0000-0002-4215-9218)
- Pardeep S. Jhund (ORCID: https://orcid.org/0000-0003-4306-5317)
- John W. Ostrominski (ORCID: https://orcid.org/0000-0002-2866-9414)
- John J.V. McMurray (ORCID: https://orcid.org/0000-0002-6317-3975)
- Katja Rohwedder
- Patrick Schloemer (ORCID: https://orcid.org/0009-0004-7787-5662)
- Meike Brinker (ORCID: https://orcid.org/0000-0002-1560-9535)
- Ian J. Kulac (ORCID: https://orcid.org/0000-0002-0710-1088)
- João Pedro Ferreira (ORCID: https://orcid.org/0000-0002-2304-6138)
- Adriaan A. Voors
- Sanjiv J. Shah (ORCID: https://orcid.org/0000-0002-5655-8201)
- Akshay S. Desai
- Scott Solomon
- Muthiah Vaduganathan
- Faïez Zannad
- B. Pitt
- Michele Senni
Institutions
- Brigham and Women's Hospital (US)
- University Medical Center Groningen (NL)
- Inserm (FR)
- University of Groningen (NL)
- Universidade do Porto (PT)
- University of Michigan (US)
- Northwestern Memorial Hospital (US)
- National Heart Centre Singapore (SG)
- French Clinical Research Infrastructure Network (FR)
- University of Milano-Bicocca (IT)
- Bayer (Germany) (DE)
- University of Glasgow (GB)
- Université de Lorraine (FR)
Publication Details
- Journal
- European Journal of Heart Failure
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1002/ejhf.70052
- Citations
- 1
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.39