Scaling up the production of fungal perylenequinones and investigating their biosynthesis through stable isotope labeling
These findings provide critical insights into optimizing fermentation conditions for the scaled and sustainable production of perylenequinones. This approach offers a cost-effective and environmentally friendly pipeline for harnessing these valuable compounds, paving the way for broader pharmaceutical and industrial applications.
Authors
- Nicholas H. Oberlies (ORCID: https://orcid.org/0000-0002-0354-8464)
- Cedric J. Pearce (ORCID: https://orcid.org/0000-0002-0212-1127)
- Shabnam Hematian (ORCID: https://orcid.org/0000-0002-0788-7615)
- Reema Al‐Qiam (ORCID: https://orcid.org/0000-0003-4776-8837)
- Huzefa A. Raja (ORCID: https://orcid.org/0000-0002-0824-9463)
- Warren S. Vidar (ORCID: https://orcid.org/0000-0003-1966-0087)
- Tyler N. Graf (ORCID: https://orcid.org/0000-0003-4145-2815)
- Sachin Dumbare
Institutions
- University of North Carolina at Greensboro (US)
- Mycosynthetix (United States) (US)
- Virginia Tech (US)
Publication Details
- Journal
- Microbial Cell Factories
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1186/s12934-025-02842-6
- Citations
- 1
- Primary Topic
- Microbial Natural Products and Biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- U.S. Department of Energy
- National Institutes of Health
- Office of Science
- National Cancer Institute
- Basic Energy Sciences