Pharmacokinetic Monitoring of <scp>JAK</scp> Inhibitor and Tacrolimus for Safe and Effective Management of Graft‐Versus‐Host Disease After Pediatric Liver Transplantation

This case illustrates the safe and effective PK-validated use of ruxolitinib with tacrolimus and posaconazole to successfully induce remission of post-LT GVHD in a pediatric patient.

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Publication Details

Journal
Pediatric Transplantation
Published
2025-10-02
DOI
https://doi.org/10.1111/petr.70187
Primary Topic
Hematopoietic Stem Cell Transplantation
Type
article
Field-Weighted Citation Impact
0.00
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article

Pharmacokinetic Monitoring of JAK Inhibitor and Tacrolimus for Safe and Effective Management of Graft‐Versus‐Host Disease After Pediatric Liver Transplantation

Tomoyuki Mizuno, Stella M. Davies, Katsunori Sawada, Akihiro Asai et al.
Pediatric Transplantation
Hematopoietic Stem Cell Transplantation
article

Pharmacokinetic Monitoring of JAK Inhibitor and Tacrolimus for Safe and Effective Management of Graft‐Versus‐Host Disease After Pediatric Liver Transplantation

Tomoyuki Mizuno, Stella M. Davies, Katsunori Sawada, Akihiro Asai, Pooja Khandelwal, Anna Crooker
article en

Abstract

This case illustrates the safe and effective PK-validated use of ruxolitinib with tacrolimus and posaconazole to successfully induce remission of post-LT GVHD in a pediatric patient.

Pediatric TransplantationVol. 29(7)
Cincinnati Children's Hospital Medical Center (US), University of Cincinnati Medical Center (US)
Openalex Percentile: Top 65%
Hematopoietic Stem Cell Transplantation
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