HMGB1-dependent signaling in the regulation of mast cell activity during inflammation
The data robustly support the notion that HMGB1 is an important endogenous alarmin that promotes and enhances MC activity in inflammatory processes. These insights highlight HMGB1 as a potential therapeutic target for regulating MC-driven inflammatory disorders, which encompass allergy, autoimmune diseases, and chronic conditions.
Authors
- Justyna Agier (ORCID: https://orcid.org/0000-0002-6759-5737)
- Margarita Jurczak (ORCID: https://orcid.org/0000-0002-5551-7707)
- Magdalena Wiktorska (ORCID: https://orcid.org/0000-0001-7346-0380)
- Paulina Żelechowska (ORCID: https://orcid.org/0000-0001-6626-3215)
- Monika Nowak (ORCID: https://orcid.org/0000-0001-6280-0722)
- Elżbieta Kozłowska (ORCID: https://orcid.org/0000-0003-2867-9126)
- Sylwia Różalska (ORCID: https://orcid.org/0000-0003-1695-5154)
Institutions
- University of Łódź (PL)
- Medical University of Lodz (PL)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-03
- DOI
- https://doi.org/10.3389/fimmu.2025.1643427
- Citations
- 2
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 2.64
Funders
- Uniwersytet Łódzki