Association between changes in obesity status and neuropsychiatric health and brain structure in different glucose status
Obesity, particularly persistent or increasing adiposity, adversely affects neuropsychiatric health and brain structure, and these effects are significantly modified by glycemic status. Our findings underscore the importance of considering glucose metabolism when assessing obesity-related brain risks, and suggest that early weight management and metabolic control may have broad benefits for preventing neuropsychiatric disorders and mitigating brain aging.
Authors
- Zhiwei Lin (ORCID: https://orcid.org/0000-0001-9194-1145)
- Wen Sun (ORCID: https://orcid.org/0000-0003-4253-8047)
- Ruilin Liu (ORCID: https://orcid.org/0009-0004-3687-3927)
- Pan Zhang (ORCID: https://orcid.org/0000-0002-5215-3135)
- Min Zou (ORCID: https://orcid.org/0000-0003-0726-1003)
- Jianmin Qiu (ORCID: https://orcid.org/0000-0003-1637-0391)
- Ping Chen (ORCID: https://orcid.org/0000-0003-3789-7686)
- Lifang Huang
Institutions
- University of Science and Technology of China (CN)
- Fujian Medical University (CN)
- Putian University (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-10-03
- DOI
- https://doi.org/10.3389/fnut.2025.1676168
- Citations
- 1
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 1.16