Accepting to Participate in an Early‐Phase Clinical Trial in Oncology: A Qualitative Study on the Patients' Experiences, Understanding, and Inner Motivations
Patients were neither delusional nor misinformed, but their decisions were shaped by complex emotional and relational dynamics. The perception of being well informed does not ensure true understanding, especially in high-stress contexts. Ambivalent emotions, tensions between expectations and hopes, and constrained choices should be considered when tailoring supportive care. Evidence-based strategies are needed to enhance communication and shared decision-making in EPCT settings.
Authors
- Anne Stoebner‐Delbarre (ORCID: https://orcid.org/0000-0002-8143-7997)
- Sylvie Dolbeault (ORCID: https://orcid.org/0000-0003-4363-2502)
- Marta Jarlier
- Estelle Guerdoux (ORCID: https://orcid.org/0000-0002-9608-0791)
- Marion Zamith‐Chavant
- Diégo Tosi (ORCID: https://orcid.org/0000-0003-0401-7400)
- Louise Coutant
- Jessica Martínez
Institutions
- Inserm (FR)
- Université de Montpellier (FR)
- Université Paris Sciences et Lettres (FR)
- Centre Hospitalier Universitaire de Montpellier (FR)
- Institut universitaire du cancer de Toulouse Oncopole (FR)
- Fondazione Bignaschi (IT)
- Institute for Neurosciences of Montpellier (FR)
- Institut de Recherche en Cancérologie de Montpellier (FR)
- Institut Curie (FR)
Publication Details
- Journal
- Psycho-Oncology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/pon.70291
- Citations
- 1
- Primary Topic
- Ethics in Clinical Research
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- Institut National de la Santé et de la Recherche Médicale
- Ligue Contre le Cancer
- Institut National Du Cancer
- Direction Générale de l’offre de Soins
- Groupement des Entreprises Françaises dans la lutte contre le Cancer