Alterations of structural–functional connectivity coupling in older adults with depressive symptoms
This study identifies alterations in SFC related to depressive symptoms in older adults, primarily within the ventral attention and subcortical networks. Subgroup analyses highlight the heterogeneous SFC changes associated with metabolic diseases and sleep disorders. These findings highlight SFC may serve as potential markers for more personalized interventions, ultimately improving the clinical management of depression in older adults.
Authors
- Shaokun Zhao (ORCID: https://orcid.org/0000-0002-0714-6024)
- Bin Peng (ORCID: https://orcid.org/0000-0001-8377-7023)
- Xin Li (ORCID: https://orcid.org/0000-0001-9598-0299)
- Baoyun Ge (ORCID: https://orcid.org/0000-0002-5807-5772)
- Haishuo Xia (ORCID: https://orcid.org/0000-0003-4970-6146)
- Zhanjun Zhang (ORCID: https://orcid.org/0000-0002-6714-3263)
- Ting Li (ORCID: https://orcid.org/0000-0003-2792-9461)
- Ziyun Li (ORCID: https://orcid.org/0000-0001-6070-6310)
- Jiawen Liu (ORCID: https://orcid.org/0000-0002-4633-2882)
Institutions
- Academy of Medical Sciences (GB)
- Army Medical University (CN)
- Peking University (CN)
- Beijing Normal University (CN)
- Beijing HuiLongGuan Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Psychological Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1017/s0033291725101657
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00