Supplementary Table 1 from Novel Afro-Caribbean Prostate Cancer Model Reveals Ancestry-Specific Drug Vulnerabilities with Therapeutic Implications for Black Patients

<p>DEGs in ACRJ-PC28 vs Other PCa. This table presents the complete list of 1396 differentially expressed genes (DEGs) identified when comparing the novel Afro-Caribbean ACRJ-PC28 cell line against all other PCa cell lines (DU-145, PC-3, and MDA-PCA-2b). For each gene, we provide the gene symbol, gene name, log2 fold change, adjusted p-value, and functional categorization. Key genes highlighted include AR, TNFRSF14, C1QTNF9B, TNFSF11, TRAF, PARP1, BRCA1/2, RAD51, and FGFR family members, which may contribute to the unique drug response profile observed in ACRJ-PC28 cells.</p>

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Publication Details

Published
2025-10-03
DOI
https://doi.org/10.1158/2767-9764.30268435
Primary Topic
Healthcare Systems and Reforms
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article
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article

Supplementary Table 1 from Novel Afro-Caribbean Prostate Cancer Model Reveals Ancestry-Specific Drug Vulnerabilities with Therapeutic Implications for Black Patients

Rajini Haraksingh, Camille Ragin, Belinda Morrison, Rory Thompson et al.
Healthcare Systems and Reforms
article

Supplementary Table 1 from Novel Afro-Caribbean Prostate Cancer Model Reveals Ancestry-Specific Drug Vulnerabilities with Therapeutic Implications for Black Patients

Rajini Haraksingh, Camille Ragin, Belinda Morrison, Rory Thompson, Bor-Jang Hwang, Simone Badal, Valerie Odero‐Marah, Ashlianne Nelson, Kristoff Frank, Magdalene Nwokocha, Tanisha Maitre
article en

Abstract

<p>DEGs in ACRJ-PC28 vs Other PCa. This table presents the complete list of 1396 differentially expressed genes (DEGs) identified when comparing the novel Afro-Caribbean ACRJ-PC28 cell line against all other PCa cell lines (DU-145, PC-3, and MDA-PCA-2b). For each gene, we provide the gene symbol, gene name, log2 fold change, adjusted p-value, and functional categorization. Key genes highlighted include AR, TNFRSF14, C1QTNF9B, TNFSF11, TRAF, PARP1, BRCA1/2, RAD51, and FGFR family members, which may contribute to the unique drug response profile observed in ACRJ-PC28 cells.</p>

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Healthcare Systems and Reforms
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Supplementary Table 1 from Novel Afro-Caribbean Prostate Cancer Model Reveals Ancestry-Specific Drug Vulnerabilities with Therapeutic Implications for Black Patients — Rajini Haraksingh, Camille Ragin, et al. · (2025) | TGRS Research Map | TGRS