Supplementary Table 1 from Novel Afro-Caribbean Prostate Cancer Model Reveals Ancestry-Specific Drug Vulnerabilities with Therapeutic Implications for Black Patients
<p>DEGs in ACRJ-PC28 vs Other PCa. This table presents the complete list of 1396 differentially expressed genes (DEGs) identified when comparing the novel Afro-Caribbean ACRJ-PC28 cell line against all other PCa cell lines (DU-145, PC-3, and MDA-PCA-2b). For each gene, we provide the gene symbol, gene name, log2 fold change, adjusted p-value, and functional categorization. Key genes highlighted include AR, TNFRSF14, C1QTNF9B, TNFSF11, TRAF, PARP1, BRCA1/2, RAD51, and FGFR family members, which may contribute to the unique drug response profile observed in ACRJ-PC28 cells.</p>
Authors
- Rajini Haraksingh (ORCID: https://orcid.org/0000-0002-6644-8874)
- Camille Ragin (ORCID: https://orcid.org/0000-0003-0816-4942)
- Belinda Morrison (ORCID: https://orcid.org/0000-0003-2271-447X)
- Rory Thompson (ORCID: https://orcid.org/0000-0002-5106-4915)
- Bor-Jang Hwang
- Simone Badal (ORCID: https://orcid.org/0000-0001-5214-3896)
- Valerie Odero‐Marah (ORCID: https://orcid.org/0000-0001-7525-4652)
- Ashlianne Nelson
- Kristoff Frank
- Magdalene Nwokocha
- Tanisha Maitre
Publication Details
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1158/2767-9764.30268435
- Primary Topic
- Healthcare Systems and Reforms
- Type
- article
- Field-Weighted Citation Impact
- 0.00