Supplementary Table 2 from Novel Afro-Caribbean Prostate Cancer Model Reveals Ancestry-Specific Drug Vulnerabilities with Therapeutic Implications for Black Patients

<p>DEGs in MDA-PCA-2b vs Other PCa. This supplementary table presents the 887 differentially expressed genes identified when comparing the Black-derived MDA-PCA-2b cell line against all other PCa cell lines (ACRJ-PC28, DU-145, and PC-3). The table includes gene symbols, descriptions, log2 fold changes, adjusted p-values, and functional classifications. Notable genes include overexpressed AR and underexpressed TNFRSF14 and TIPARP, along with members of growth factor families (VEGFC, FGF2, EGFLAM, HBEGF, and EGFL7) that may influence the cell line's unique response to targeted therapies, particularly its resistance to Olaparib and reduced sensitivity to Enzalutamide.</p>