Defining the Stem Cell Niche in Developing Pericoronal Dental Follicles
The dental follicle contains a population of stem cells with a specific phenotype capable of multilineage differentiation. It may represent another promising source of human adult stem cells. The observed differentiation profile may limit the application of the isolated cells in the hard tissue regeneration and suggest a potentially more suitable role in soft tissue engineering or immunomodulatory therapies.
Authors
- Zornitsa Mihaylova (ORCID: https://orcid.org/0000-0003-1748-4489)
- Vanio Mitev (ORCID: https://orcid.org/0000-0001-7528-590X)
- Evgeniy Aleksiev (ORCID: https://orcid.org/0000-0002-9656-1106)
- Riana Cockeran
- Silvia Kalenderova (ORCID: https://orcid.org/0000-0001-5349-6095)
- Nikolay Ishkitiev (ORCID: https://orcid.org/0000-0002-4351-5579)
- Marina Miteva (ORCID: https://orcid.org/0000-0002-3910-5147)
- Maria Praskova (ORCID: https://orcid.org/0000-0002-8149-9039)
- Violeta Dimitrova (ORCID: https://orcid.org/0009-0006-8649-2051)
Institutions
- Medical University of Sofia (BG)
- South African National Blood Service (ZA)
Publication Details
- Journal
- Cureus
- Published
- 2025-10-02
- DOI
- https://doi.org/10.7759/cureus.93712
- Primary Topic
- Oral and Maxillofacial Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00