Arctigenin from Saussurea medusa Maxim. Targets the PI3K/AKT Pathway to Inhibit Hepatocellular Carcinoma Proliferation and Induces Apoptosis

These findings suggest ARC suppresses HCC by modulating the PI3K/AKT pathway, providing evidence for its development as a plant-derived therapeutic agent.

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Publication Details

Journal
Nutrients
Published
2025-10-02
DOI
https://doi.org/10.3390/nu17193151
Citations
1
Primary Topic
Plant-derived Lignans Synthesis and Bioactivity
Type
article
Field-Weighted Citation Impact
0.81
Controls
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article

Arctigenin from Saussurea medusa Maxim. Targets the PI3K/AKT Pathway to Inhibit Hepatocellular Carcinoma Proliferation and Induces Apoptosis

Ruitao Yu, Ruixue Yu, Jinghua Chen
1 citations
Nutrients
Plant-derived Lignans Synthesis and Bioactivity
0.81
article

Arctigenin from Saussurea medusa Maxim. Targets the PI3K/AKT Pathway to Inhibit Hepatocellular Carcinoma Proliferation and Induces Apoptosis

Ruitao Yu, Ruixue Yu, Jinghua Chen
article en
1 citations

Abstract

These findings suggest ARC suppresses HCC by modulating the PI3K/AKT pathway, providing evidence for its development as a plant-derived therapeutic agent.

NutrientsVol. 17(19)
Pingdingshan University (CN), University of Chinese Academy of Sciences (CN)
Openalex Percentile: Top 23%
Plant-derived Lignans Synthesis and Bioactivity
0.81
DOIOpen Access PDFOpenAlex
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Arctigenin from Saussurea medusa Maxim. Targets the PI3K/AKT Pathway to Inhibit Hepatocellular Carcinoma Proliferation and Induces Apoptosis — Ruitao Yu, Ruixue Yu, et al. · Nutrients (2025) | TGRS Research Map | TGRS