World’s Largest Neglected Parosteal Lipoma Presenting as Deep Vein Thrombosis of the Lower Limb: An Extremely Rare Presentation

Background: Parosteal lipomas are rare benign tumors of adipose tissue located on the cortical surface of bone.They represent only a small fraction of bone lipomas, and most reported cases are small and incidentally detected.Presentation with deep vein thrombosis (DVT) has not been described previously.Case Report: We present a 61-year-old male with acute right lower limb pain diagnosed as popliteal vein DVT.Evaluation revealed a giant 30 cm parosteal lipoma of the femur, the largest reported to date.The lesion was completely excised, and the patient made an uneventful recovery with no recurrence on long-term follow-up.Conclusion: This case describes to best of our knowledge the world's largest parosteal lipoma and its unusual presentation with DVT.Complete surgical excision through a multidisciplinary approach is essential for cure and to prevent recurrence.