Case Report: Two cases of chronic active Epstein-Barr virus disease presenting as refractory sinusitis
This rare case report describes two cases of systemic CAEBV presenting as refractory sinusitis. The report also shows the potential of CAR-T as a treatment for CAEBV. We comprehensively reviewed the diagnostic and therapeutic trajectories of both patients from disease onset, hoping to provide reference for clinical practice.
Authors
- Shuman Huang (ORCID: https://orcid.org/0000-0001-5411-743X)
- Puyu Wang (ORCID: https://orcid.org/0000-0001-5198-8803)
- Hui Zhang (ORCID: https://orcid.org/0000-0001-7267-5179)
- Dong Dong (ORCID: https://orcid.org/0000-0002-7700-4232)
- Yuanyuan Li (ORCID: https://orcid.org/0000-0001-8467-9759)
- Yulin Zhao (ORCID: https://orcid.org/0009-0003-7792-1166)
- Linyuan Wang (ORCID: https://orcid.org/0000-0002-9048-2829)
Institutions
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-02
- DOI
- https://doi.org/10.3389/fimmu.2025.1678519
- Primary Topic
- Viral-associated cancers and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Zhengzhou University