Palliative effect of taurine against hepatic injury induced by polystyrene microplastics through antioxidant and metabolic pathway modulation in mice
Overall, the findings indicated that PS-MPs caused liver damage via oxidative stress and lipid metabolic disturbance, and that Tau supplementation had a protective effect, possibly via modulating oxidative and metabolic pathways. This experiment emphasized the necessity for additional research into Tau as a therapeutic agent in microplastic-related liver damage.
Authors
- Nawal Alsubaie
- Leena S. Alqahtani (ORCID: https://orcid.org/0000-0003-1789-2239)
- Yasmina M. Abd‐Elhakim (ORCID: https://orcid.org/0000-0002-3646-6385)
- Amany Abdel-Rahman Mohamed (ORCID: https://orcid.org/0000-0003-0061-2675)
- Badriyah S. Alotaibi (ORCID: https://orcid.org/0000-0002-4066-5694)
- Tarek Khamis (ORCID: https://orcid.org/0000-0003-4722-2666)
- Ahmed E. Abdelhamid (ORCID: https://orcid.org/0000-0002-1421-366X)
- Ahmed E. Noreldin (ORCID: https://orcid.org/0000-0002-8344-0807)
- Areej A. Eskandrani
Institutions
- Princess Nourah bint Abdulrahman University (SA)
- Damanhour University (EG)
- Zagazig University (EG)
- Taibah University (SA)
- University of Jeddah (SA)
- National Research Centre (EG)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-10-02
- DOI
- https://doi.org/10.3389/fphar.2025.1665161
- Citations
- 2
- Primary Topic
- Microplastics and Plastic Pollution
- Type
- article
- Field-Weighted Citation Impact
- 1.01
Funders
- Princess Nourah Bint Abdulrahman University