Bacteriophage combined with mNGS enhances the specificity of bacterial infection diagnosis
In sepsis, compared with conventional mNGS methods alone, the use of bacteriophages combined with mNGS was more effective in identifying causative pathogens and had higher specificity. These findings may provide new ideas and tools for improving clinical infection diagnosis.
Authors
- Guangtao Huang (ORCID: https://orcid.org/0000-0003-0285-2381)
- Ying Liu (ORCID: https://orcid.org/0000-0001-6718-7381)
- Lu Wang (ORCID: https://orcid.org/0000-0002-9303-4482)
- Yafeng Zheng
- Jinyan Xing (ORCID: https://orcid.org/0000-0001-8575-3949)
- Yuxin Guo (ORCID: https://orcid.org/0000-0002-3473-3240)
- Zhiyong Yuan (ORCID: https://orcid.org/0000-0001-9608-6037)
- Wei Gai (ORCID: https://orcid.org/0009-0003-3002-4142)
- Fuhua Wang
Institutions
- Qingdao University (CN)
- Beijing Founder Electronics (China) (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- Journal of Infection
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.jinf.2025.106618
- Citations
- 1
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 1.72