Genetic Architecture of Cerebral White Matter Hyperintensities in Diverse Hispanic/Latino Adults
Our study suggests that WMH loci previously identified in NHW and AA individuals are relevant to Hispanic/Latino adults. It demonstrates the power of the diverse Hispanic/Latino population to fine-map known genetic loci and discover novel ones, augmenting our understanding of the genetic architecture of cerebral WMHs.
Authors
- Richard B. Lipton (ORCID: https://orcid.org/0000-0003-2652-2897)
- Tamar Sofer (ORCID: https://orcid.org/0000-0001-8520-8860)
- Carmen R. Isasi (ORCID: https://orcid.org/0000-0003-2700-9593)
- Adriana López (ORCID: https://orcid.org/0000-0001-9169-800X)
- Hector M. González (ORCID: https://orcid.org/0000-0003-4867-7902)
- Charles S DeCarli (ORCID: https://orcid.org/0000-0003-1914-2693)
- Wassim Tarraf (ORCID: https://orcid.org/0000-0001-8888-7918)
- Ariana M. Stickel (ORCID: https://orcid.org/0000-0002-6312-2377)
- Rui Xia (ORCID: https://orcid.org/0000-0002-5614-640X)
- Myriam Fornage (ORCID: https://orcid.org/0000-0003-0677-8158)
Institutions
- Brigham and Women's Hospital (US)
- Albert Einstein College of Medicine (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Wayne State University (US)
- San Diego State University (US)
- University of California San Diego (US)
- Brown Foundation (US)
- University of California, Davis (US)
Publication Details
- Journal
- Neurology Genetics
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1212/nxg.0000000000200305
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Gillings School of Public Health