<b>Histological evaluation of thermosensory receptors and cutaneous neurovascular in the tail skin of BALB/c mice</b>

Thermal stimulation activates both peripheral and central pathways involving thermoreceptors, neuropeptides, and gene regulation. This study also shows how simple thermal exposure can alter nerve density and neurochemical signals. Thermal stimuli activate clear histological, molecular, and epigenetic responses in BALB/c mice that link the skin and brain.