<b>Pharmacokinetics, pharmacodynamic efficacy prediction indices, and Monte Carlo simulations of enrofloxacin for the treatment of colibacillosis in broiler chickens</b>
The PK/PD approach applied in Cobb broiler chickens demonstrates the potential for dose optimization based on MIC distribution, supporting Antimicrobial Stewardship efforts. However, further complementary studies are required to evaluate the predictive capabilities of these indices and to establish the optimal PK/PD targets for <i>in vivo</i> efficacy.
Authors
- Marcos Ferrante (ORCID: https://orcid.org/0000-0001-6979-2956)
- Márcio Gilberto Zangerônimo
- Sheila Wosiacki (ORCID: https://orcid.org/0000-0002-3882-8327)
- Luís Félix (ORCID: https://orcid.org/0000-0002-1758-372X)
- Beatriz Monte Egito (ORCID: https://orcid.org/0000-0002-3019-0824)
- D. C. Díaz David
Institutions
- Universidade Estadual de Maringá (BR)
- Universidade Federal de Lavras (BR)
- Universidad Nacional del Litoral (AR)
Publication Details
- Journal
- Open Veterinary Journal
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5455/ovj.2025.v15.i9.52
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00