<b>Global dynamics of vaccine effectiveness and genotype shift in porcine circovirus 2: A cross-temporal analysis</b>

PCV2 vaccination exerts selective pressure driving genotype succession. The accelerated waning of protection against emergent genotypes and the emergence of escape-associated mutations at key antigenic sites support the development of multivalent vaccines incorporating PCV2d antigens to sustain long-term herd immunity.

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Publication Details

Journal
Open Veterinary Journal
Published
2025-01-01
DOI
https://doi.org/10.5455/ovj.2025.v15.i9.40
Primary Topic
Animal Virus Infections Studies
Type
article
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article

Global dynamics of vaccine effectiveness and genotype shift in porcine circovirus 2: A cross-temporal analysis

Fredmoore L. Orosco
Open Veterinary Journal
Animal Virus Infections Studies
article

Global dynamics of vaccine effectiveness and genotype shift in porcine circovirus 2: A cross-temporal analysis

Fredmoore L. Orosco
article en

Abstract

PCV2 vaccination exerts selective pressure driving genotype succession. The accelerated waning of protection against emergent genotypes and the emergence of escape-associated mutations at key antigenic sites support the development of multivalent vaccines incorporating PCV2d antigens to sustain long-term herd immunity.

Open Veterinary JournalVol. 15(9)
Department of Science and Technology (PH)
Openalex Percentile: Top 69%
Animal Virus Infections Studies
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<b>Global dynamics of vaccine effectiveness and genotype shift in porcine circovirus 2: A cross-temporal analysis</b> — Fredmoore L. Orosco · Open Veterinary Journal (2025) | TGRS Research Map | TGRS