Behavioral dynamics of social propagation for weight loss: Evidence from a randomized controlled trial in a low-income Appalachian community

Leveraging social propagation of health interventions for disease prevention is a public health holy grail. However, the dynamics of social causal induction have not been well studied. We present evidence from a randomized trial, demonstrating social-behaviorally “infectious” risk factor dynamics for obesity and diabetes. Specifically, we present the Social R 0 of weight loss propagation, which is itself adapted from the widely used infectious disease R 0 . Via the trial design to infer causality, we calculated the Social R 0 across multiple time points for weight change propagation ( social-R 0 = 1.2, p < 0.01). We further show that health propagation of an intervention program can attain epidemic proportions; and that public health systems can intervene to modify the R 0 value thereby potentially managing, preventing, or reversing social infections at epidemic scale (yielding population-averaged comparative R 0 ratios, 7.77 < R c < 15.58, p < 0.01, for weight loss propagation). To facilitate adoption of the methodologies, macros and code for use with various statistical software packages are included. The results indicate that the social induction of health interventions are not only possible, but that propagation can both be isolated causally via trial design and be quantified over time. This bodes enormous promise for developing and quantifying future self-sustaining public health interventions.

Authors

Institutions

Publication Details

Journal
PLOS complex systems.
Published
2025-10-02
DOI
https://doi.org/10.1371/journal.pcsy.0000068
Primary Topic
Obesity, Physical Activity, Diet
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Behavioral dynamics of social propagation for weight loss: Evidence from a randomized controlled trial in a low-income Appalachian community

Daniel E. Zoughbie, Dillon Huddleston, Eric L. Ding
PLOS complex systems.
Obesity, Physical Activity, Diet
article

Behavioral dynamics of social propagation for weight loss: Evidence from a randomized controlled trial in a low-income Appalachian community

Daniel E. Zoughbie, Dillon Huddleston, Eric L. Ding
article en

Abstract

Leveraging social propagation of health interventions for disease prevention is a public health holy grail. However, the dynamics of social causal induction have not been well studied. We present evidence from a randomized trial, demonstrating social-behaviorally “infectious” risk factor dynamics for obesity and diabetes. Specifically, we present the Social R 0 of weight loss propagation, which is itself adapted from the widely used infectious disease R 0 . Via the trial design to infer causality, we calculated the Social R 0 across multiple time points for weight change propagation ( social-R 0 = 1.2, p < 0.01). We further show that health propagation of an intervention program can attain epidemic proportions; and that public health systems can intervene to modify the R 0 value thereby potentially managing, preventing, or reversing social infections at epidemic scale (yielding population-averaged comparative R 0 ratios, 7.77 < R c < 15.58, p < 0.01, for weight loss propagation). To facilitate adoption of the methodologies, macros and code for use with various statistical software packages are included. The results indicate that the social induction of health interventions are not only possible, but that propagation can both be isolated causally via trial design and be quantified over time. This bodes enormous promise for developing and quantifying future self-sustaining public health interventions.

PLOS complex systems.Vol. 2(10)
Microclinic International (US), New England Complex Systems Institute (US)
Openalex Percentile: Top 63%
Obesity, Physical Activity, Diet
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.