A Dual-Drug Nanosuspension of Bufalin and Quercetin Exhibits Potent Anti-Hepatocellular Carcinoma Activity In vitro and In vivo
The prepared BF-QUE NS enhanced the drug solubility and promoted the targeted accumulation in tumors, thereby strengthening the synergistic anti-tumor effect of BF and QUE. BFQUE NS shows potential for clinical application as an anti-liver tumor drug.
Authors
- Tiantian Zhu (ORCID: https://orcid.org/0000-0001-9017-6680)
- Ruirui Song (ORCID: https://orcid.org/0000-0002-3393-2985)
- Chengcheng Gao (ORCID: https://orcid.org/0000-0002-9309-8793)
- Zerun Yang
- Bingqian Li (ORCID: https://orcid.org/0000-0002-3359-8200)
- Huagang Sheng (ORCID: https://orcid.org/0000-0003-2299-7553)
- Liqiao Zhu
- Yan Sun (ORCID: https://orcid.org/0000-0001-7570-1002)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Current Drug Delivery
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2174/0115672018405334250831225746
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00