Assessment of the Values of Endoglin and Soluble Fms-Like Tyrosine Kinase-1/Placental Growth Factor Ratio Among Women at Risk for Pre-eclampsia: A Cross-Sectional Study

This study highlights the clinical significance of serum endoglin and sFlt-1/PlGF ratio levels in women at high risk for PE. Elevated serum endoglin and SFlt-1/PlGF ratio levels were found to be strongly associated with women at high risk for PE. Hence, it can be used as a potential biomarker for detecting the high risk for PE at 24 to 28 weeks. This study suggested that using a combination of the above two markers (endoglin and Sflt-1/PGLF ratio) will have a high sensitivity of 100% (43.7-100) and a specificity of 71.9% (58.9-82.3).