The Challenge of Hypophosphatasia Diagnosis in Patients with Fibromyalgia
In the present cohort, 3.2% presented persistently decreased ALP levels. The increased ALPL substrate, PLP, observed in one third of these subjects, together with the negative genetic study in all these subjects, indicate the need to better identify the subjects with FM that may have mild forms of HPP.
Authors
- C. Adão
- Chafik Chacur (ORCID: https://orcid.org/0000-0001-6781-0153)
- Xavier Torres (ORCID: https://orcid.org/0000-0002-7442-8750)
- Helena Flórez (ORCID: https://orcid.org/0000-0002-9375-5634)
- Pilar Peris (ORCID: https://orcid.org/0000-0003-1311-451X)
- Anastasia Mocritcaia (ORCID: https://orcid.org/0009-0002-9667-6883)
- Tamara L. Rodríguez-Araya (ORCID: https://orcid.org/0000-0002-2540-1455)
- Luciano Polino
- Eva González‐Roca (ORCID: https://orcid.org/0000-0002-1126-0321)
- Anna Arias
- Maria Belen Busso
Institutions
- Hospital Clínic de Barcelona (ES)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Medical Principles and Practice
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1159/000548638
- Primary Topic
- Alkaline Phosphatase Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00