Tumour‐infiltrating lymphocytes, tertiary lymphoid structures and myxoid stroma predict upstaging of ductal carcinoma in situ in breast biopsies
Stromal TILs, TLSs and myxoid stroma are robust predictors of upstaging to invasive carcinoma in patients diagnosed with ADH/DCIS on biopsy. These features can be readily assessed by pathologists using only H&E staining and should be considered in future risk stratification models to inform clinical decision-making.
Authors
- Chung‐Yen Huang (ORCID: https://orcid.org/0000-0001-9691-9537)
- Min‐Shu Hsieh (ORCID: https://orcid.org/0000-0002-0594-3732)
- Yi‐Hsuan Lee (ORCID: https://orcid.org/0000-0002-2995-8306)
- Yu‐Jui Wang (ORCID: https://orcid.org/0009-0001-5537-4486)
- Pin‐Yu Lin
Institutions
- National Taiwan University (TW)
- National Taiwan University Hospital (TW)
Publication Details
- Journal
- Histopathology
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1111/his.70009
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00