Upregulation of GLT-1 Expression Attenuates Neuronal Apoptosis and Cognitive Dysfunction via Inhibiting the CB1-CREB Signaling Pathway in Mice with Traumatic Brain Injury
Our research demonstrated that the upregulation of GLT-1 expression effectively mitigated neuronal apoptosis and cognitive dysfunction by inhibiting the CB1-CREB signaling pathway. This finding may offer a promising therapeutic strategy for TBI.
Authors
- Bin Bu
- Ruiyao Ma
- Chengyu Wang (ORCID: https://orcid.org/0000-0002-6337-489X)
- Xiaoming Xu (ORCID: https://orcid.org/0000-0003-4779-1316)
- Shukun Jiang
Institutions
- Shanghai Public Security Bureau (CN)
- Institute of Forensic Science (CN)
- First Hospital of China Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Biomolecules
- Published
- 2025-10-02
- DOI
- https://doi.org/10.3390/biom15101408
- Citations
- 2
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 2.33
Funders
- China Medical University