The Implantable Electrode Co-Deposited with Iron Oxide Nanoparticles and PEDOT:PSS

Iron oxide nanoparticles (IONs) exhibit biocompatibility, ease of drug loading, and potential for generating forces and heat in a magnetic field, enhancing Magnetic Resonance Imaging (MRI). This study proposes coating IONs on electrode surfaces to improve performance and neuron bonding. Methods included synthesizing IONs, grafting chondroitin sulfate (CS), and co-depositing with poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS). Results showed reduced impedance, increased charge storage, and improved signal quality in vivo.