A novel role of liquid plasma (LP) induced RONS triggers the endoplasmic reticulum stress response and is associated with GSDME-mediated pyroptosis in anaplastic thyroid cancer
LP induces pyroptosis via GSDME activation and RONS generation in vitro and in vivo in ATC models, suggesting a novel mechanism and indicating a potential chemotherapeutic approach for the treatment of ATC.
Authors
- Eun Jong Ji
- Se Hyun Yeou (ORCID: https://orcid.org/0000-0002-0827-479X)
- Chul‐Ho Kim (ORCID: https://orcid.org/0000-0002-2161-4488)
- Sung Un Kang
Institutions
- Il-Yang Pharmaceutical (South Korea) (KR)
- Ajou University (KR)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1186/s12964-025-02397-4
- Citations
- 1
- Primary Topic
- Heme Oxygenase-1 and Carbon Monoxide
- Type
- article
- Field-Weighted Citation Impact
- 0.81