Current status and solutions for AI ethics in ophthalmology: a bibliometric analysis
Ophthalmology, an early adopter of medical artificial intelligence (AI), has made significant advancements, but ethical discussions limited. This bibliometric analysis reviewed 498 publications from Web of Science and Scopus (2000-2023) to explore the evolution, status, thematic trends, data modalities and their ethical focus, and solutions in ophthalmic AI ethics. Ophthalmology ranks second in medical AI ethics, with major contributors from the United States (US), China, the United Kingdom (UK), Singapore and India. Ethical concerns focus on privacy, fairness, and transparency. Ethical priorities differ by modality with fundus imaging (59.4%) and Optical Coherence Tomography (OCT) (30.9%) as the most common. Most studies (78.3%) address ethics in diagnostic algorithm development, while only 11.5% directly target ethical concerns, though this focus is increasing. This study highlights the need for AI technologies and guidelines to address ethical challenges in ophthalmology, offering a future direction for research and innovation in medical AI governance.
Authors
- Lingyi Liang
- Yahan Yang (ORCID: https://orcid.org/0009-0008-6098-3244)
- Yu‐Chun Lin (ORCID: https://orcid.org/0000-0002-9629-7560)
- Ruixin Wang (ORCID: https://orcid.org/0000-0002-4395-8492)
- Matthew J. Burton (ORCID: https://orcid.org/0000-0003-1872-9169)
- Weixing Zhang (ORCID: https://orcid.org/0000-0003-1459-1043)
- Mingjie Luo (ORCID: https://orcid.org/0000-0001-7482-4975)
- Patrick Yu‐Wai‐Man
- Xinwei Chen (ORCID: https://orcid.org/0000-0002-3376-415X)
- Haotian Lin (ORCID: https://orcid.org/0009-0003-1173-4202)
- Dongyuan Yun
Institutions
- Sun Yat-sen University (CN)
- University of Cambridge (GB)
- London School of Hygiene & Tropical Medicine (GB)
- Hainan Eye Hospital (CN)
- Addenbrooke's Hospital (GB)
- MRC Mitochondrial Biology Unit (GB)
Publication Details
- Journal
- npj Digital Medicine
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1038/s41746-025-01976-6
- Citations
- 3
- Primary Topic
- Artificial Intelligence in Healthcare and Education
- Type
- article
- Field-Weighted Citation Impact
- 1.96
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Science and Technology Planning Project of Guangdong Province