Future outcomes and current limitations of injectable implants for vocal fold scarring
The review highlights the ongoing research on injections of implants for VF scarring that support biomechanical properties and modulate local tissue repair. However, further advanced and long-term studies, including clinical trials, are needed to fully elucidate their safety, efficacy, and toxicity profiles. In addition, their scalability and reproducibility within pharmaceutical manufacturing must be rigorously validated to support clinical translation.
Authors
- Sapir Pinhas (ORCID: https://orcid.org/0000-0002-2598-4929)
- Peter J. Larson (ORCID: https://orcid.org/0000-0002-2806-284X)
- D. Cruz (ORCID: https://orcid.org/0000-0002-1289-6962)
- Gregory R. Dion (ORCID: https://orcid.org/0000-0003-4389-3104)
- Nour Awad
- Luigi Melaragno
Institutions
- Applied Science Private University (JO)
- University of Cincinnati (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Expert Opinion on Drug Delivery
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1080/17425247.2025.2569640
- Primary Topic
- Voice and Speech Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00