RSL3 promotes PARP1 apoptotic functions by distinct mechanisms during ferroptosis
RSL3 orchestrates ferroptosis-apoptosis crosstalk via PARP1, demonstrating therapeutic potential against tumorigenesis, particularly in PARPi-resistant malignancies.
Authors
- Dejian Chen (ORCID: https://orcid.org/0000-0002-4547-7916)
- Lingyan Chen (ORCID: https://orcid.org/0000-0002-1871-2060)
- Fei Xie (ORCID: https://orcid.org/0000-0003-0505-0229)
- Qin Du (ORCID: https://orcid.org/0000-0003-2960-5575)
- Zheng Binjiao
- Yimei Mo
Institutions
- Wenzhou Medical University (CN)
- Guangzhou Psychiatric Hospital (CN)
- Guangdong 999 Brain Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Cellular & Molecular Biology Letters
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1186/s11658-025-00785-9
- Citations
- 5
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- Wenzhou Medical University
- Guangzhou Medical University
- University of Alberta
- University of South China