Impact of Low-Intensity Ultrasound on Pediatric Dural Cells: Implications for Calvarial Repair
Dural cells express characteristic stem cell markers but do not undergo osteogenic differentiation after chemical or mechanical stimulation; however, ultrasound treatment upregulates elements of the Wnt paracrine signaling pathway, suggesting a novel mechanism that might be harnessed to improve outcomes after autologous cranioplasty.
Authors
- Hanna Anderson (ORCID: https://orcid.org/0000-0002-4430-5602)
- Yusuf Khan (ORCID: https://orcid.org/0000-0003-3792-3477)
- David S. Hersh (ORCID: https://orcid.org/0000-0003-1177-2201)
Institutions
- University of Connecticut (US)
- Connecticut Children's Medical Center (US)
- Hartford Financial Services (United States)
- UConn Health (US)
Publication Details
- Journal
- Neurosurgery
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1227/neu.0000000000003787
- Primary Topic
- Craniofacial Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00