Exploring Alice in Wonderland syndrome in adults with persistent headache after COVID-19: a cross-sectional study in Latin America
In this cohort, AIWS was a notable feature in adults with persistent headache after COVID-19, particularly in younger individuals with a history of migraine. Experiencing AIWS symptoms during acute infection increased the odds of post-acute AIWS symptoms nearly tenfold, suggesting SARS-CoV-2 may be a potent trigger. Clinicians should be aware of this association and screen for perceptual disturbances in patients with post-COVID-19 neurological sequelae.
Authors
- Óscar D. Omaña‐Ávila (ORCID: https://orcid.org/0000-0002-4505-215X)
- Alberto Paniz‐Mondolfi (ORCID: https://orcid.org/0000-0003-1259-1736)
- David A. Forero‐Peña (ORCID: https://orcid.org/0000-0002-8065-8464)
- Natasha A. Camejo‐Ávila (ORCID: https://orcid.org/0000-0001-9131-7852)
- Daniela L. Mendoza-Millán
- Luis C. Ascanio (ORCID: https://orcid.org/0000-0001-9914-1599)
- Fhabián S. Carrión‐Nessi (ORCID: https://orcid.org/0000-0003-4415-8646)
- Oriana A. Regalado-Gutiérrez
Institutions
- Bolivarian University of Venezuela (VE)
- Hospital Clínico Universitario de Caracas (VE)
- Incubadora Venezolana de la Ciencia (VE)
- Universidad Central de Venezuela (VE)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- BMC Neurology
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1186/s12883-025-04422-y
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.00