Semiheterogeneous Intrinsic FeTiO<sub>3</sub>-Photoredox/Ph<sub>3</sub>N Dual-Catalyzed Fluoroalkylation of N-Heteroarenes with Alkenes and R<sub>f</sub>SO<sub>2</sub>Cl
Herein, we report the sustainable semiheterogeneous synthesis of various fluoroalkylated <i>N</i>-heteroarenes using natural intrinsic iron(II) titanium oxide (FeTiO<sub>3</sub>) as a semiconductor photocatalyst and Ph<sub>3</sub>N as a redox mediator. This synergistic system combines photogenerated electron-mediated fluoroalkyl sulfonyl chloride (R<sub>f</sub>SO<sub>2</sub>Cl) reduction with photogenerated hole-induced oxidative dehydrogenation aromatization, enabling high-yielding transformations with excellent functional-group tolerance while avoiding stoichiometric redox reagents or sacrificial electron donors/acceptors.
Authors
- Chunlin Zhuang (ORCID: https://orcid.org/0000-0002-0569-5708)
- Wei‐Min He (ORCID: https://orcid.org/0000-0002-9481-6697)
- Shenghua Wang (ORCID: https://orcid.org/0000-0002-4821-4580)
- Qiong-Hui Peng
- Jun Rong Jiang (ORCID: https://orcid.org/0000-0002-5542-7592)
- Yue Cai (ORCID: https://orcid.org/0000-0002-3711-5325)
- Zi Yang (ORCID: https://orcid.org/0000-0002-8377-118X)
- Zu‐Li Wang (ORCID: https://orcid.org/0000-0002-3503-4097)
- Hui Dai
Institutions
- Changsha Medical University (CN)
- Nanjing Forestry University (CN)
- University of South China (CN)
- Hunan Institute of Technology (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1021/acs.joc.5c02000
- Citations
- 7
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 5.54