Spatiotemporal analysis of dystrophin expression during muscle repair
Our data demonstrate that dystrophin mRNA is indeed chiefly controlled by turnover, not initiation: degradation consequently represents a potential therapeutic target for maximising efficacy of even modest dystrophin restoration.
Authors
- Dominic J. Wells (ORCID: https://orcid.org/0000-0002-1425-6344)
- John Hildyard (ORCID: https://orcid.org/0000-0003-2283-2118)
- Richard J. Piercy (ORCID: https://orcid.org/0000-0002-4344-6438)
- Liberty E. Roskrow
Institutions
- Royal Veterinary College (GB)
Publication Details
- Journal
- Skeletal Muscle
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1186/s13395-025-00398-y
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00