The difficulties of differential diagnosis of primary lymphoma and toxoplasmous encephalitis in a patient with HIV-associated encephalopathy

The article discusses aspects of the differential diagnosis of primary lymphoma of the central nervous system and toxoplasmous encephalitis in a patient with HIV-associated encephalopathy. Both diseases have similar clinical manifestations, which makes differential diagnosis difficult. However, an in-depth study of clinical and anamnestic data, modern neuroimaging methods such as contrast-enhanced MRI, and awareness of radiologists about the specific signs of these diseases significantly improve the early diagnosis of these nosology’s.

Authors

Publication Details

Journal
Clinical review for general practice
Published
2025-04-26
DOI
https://doi.org/10.47407/kr2025.6.4.00589
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
0.00
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article

The difficulties of differential diagnosis of primary lymphoma and toxoplasmous encephalitis in a patient with HIV-associated encephalopathy

Olga V. Kurushina, V. V. Miroshnikova, П. С. Кривоножкина, Olga V. Pokusaeva et al.
Clinical review for general practice
Cytomegalovirus and herpesvirus research
article

The difficulties of differential diagnosis of primary lymphoma and toxoplasmous encephalitis in a patient with HIV-associated encephalopathy

Olga V. Kurushina, V. V. Miroshnikova, П. С. Кривоножкина, Olga V. Pokusaeva, Dmitry I. Nezhinsky
article en

Abstract

The article discusses aspects of the differential diagnosis of primary lymphoma of the central nervous system and toxoplasmous encephalitis in a patient with HIV-associated encephalopathy. Both diseases have similar clinical manifestations, which makes differential diagnosis difficult. However, an in-depth study of clinical and anamnestic data, modern neuroimaging methods such as contrast-enhanced MRI, and awareness of radiologists about the specific signs of these diseases significantly improve the early diagnosis of these nosology’s.

Clinical review for general practiceVol. 6(4)
Openalex Percentile: Top 63%
Cytomegalovirus and herpesvirus research
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