R WE ready for reimbursement? A round-up of developments in real-world evidence relating to health technology assessment: part 21
In this update, we explore the vocal adoption of the target trial emulation framework by the US FDA, the FRAME methodology for systematically evaluating the use and impact of RWE in health technology assessment and regulatory submissions, and the Canadian CanREValue framework for incorporating RWE into cancer medicine reassessment decisions.
Authors
- Sreeram V Ramagopalan (ORCID: https://orcid.org/0000-0002-4766-5160)
- Paul Arora (ORCID: https://orcid.org/0000-0001-6617-3631)
Institutions
- King's College London (GB)
- University of Toronto (CA)
- Public Health Ontario (CA)
Publication Details
- Journal
- Journal of Comparative Effectiveness Research
- Published
- 2025-10-02
- DOI
- https://doi.org/10.57264/cer-2025-0148
- Citations
- 2
- Primary Topic
- Health Systems, Economic Evaluations, Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 6.26