Association of IGF-1 with hypertension among children and adolescents
Lower IGF-1 levels are significantly associated with an increased risk of hypertension in children and adolescents. This association is evident across different subgroups, including sex, age, and obesity status. These findings highlight Maintaining the balance of these factors is critical for hypertension health, especially during adolescence.
Authors
- Ye Cao (ORCID: https://orcid.org/0000-0001-7663-1480)
- Pengfei Xie (ORCID: https://orcid.org/0000-0002-7644-9934)
- Zhong‐Ze Fang (ORCID: https://orcid.org/0000-0003-1113-9262)
- Ting Huang
- Zhenghao Zhao (ORCID: https://orcid.org/0009-0000-1934-4661)
- Xinyi Zhang (ORCID: https://orcid.org/0000-0003-3133-6271)
- Yan Liu (ORCID: https://orcid.org/0000-0002-4640-716X)
- Yue Wen
Institutions
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Chinese PLA General Hospital (CN)
- Tianjin Medical University Eye Hospital (CN)
- Shanghai Institute of Pharmaceutical Industry (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- BMC Pediatrics
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1186/s12887-025-06007-7
- Primary Topic
- Growth Hormone and Insulin-like Growth Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China