Analysis of human endogenous retrovirus in hepatocellular carcinomas using HERV-Fcount

HERV-Fcount detects HERVs faster than the Telescope. In addition to total RNA-seq, which increases the detection of HERVs and their nearby genes, this phenomenon can also be observed with HERV-Fcount. HERVs activation results in dysregulation of nearby genes that could be associated with HCC development and prognosis.

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Publication Details

Journal
BMC Microbiology
Published
2025-10-02
DOI
https://doi.org/10.1186/s12866-025-04358-w
Primary Topic
Chromosomal and Genetic Variations
Type
article
Field-Weighted Citation Impact
0.00

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article

Analysis of human endogenous retrovirus in hepatocellular carcinomas using HERV-Fcount

Ya‐Sian Chang, Ya-Ting Lee, Ming-Hon Hsu, Jan‐Gowth Chang et al.
BMC Microbiology
Chromosomal and Genetic Variations
article

Analysis of human endogenous retrovirus in hepatocellular carcinomas using HERV-Fcount

Ya‐Sian Chang, Ya-Ting Lee, Ming-Hon Hsu, Jan‐Gowth Chang, Chin‐Chun Chung, Chieh‐Min Chang, Ju-Chen Yen, I‐Lu Lai, Ta‐Chih Liu
article en

Abstract

HERV-Fcount detects HERVs faster than the Telescope. In addition to total RNA-seq, which increases the detection of HERVs and their nearby genes, this phenomenon can also be observed with HERV-Fcount. HERVs activation results in dysregulation of nearby genes that could be associated with HCC development and prognosis.

BMC MicrobiologyVol. 25(1)
Asia University (TW), China Medical University (TW), Hualien Tzu Chi Medical Center (TW), Chang Bing Show Chwan Memorial Hospital (TW)
China Medical University Hospital, Ministry of Science and Technology, Taiwan, China Medical University, Chang Bing Show Chwan Memorial Hospital, Division of Materials Research
Openalex Percentile: Top 80%
Chromosomal and Genetic Variations
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