Analgesic efficacy of 7 different topical NSAIDs in panretinal photocoagulation-associated pain

Bromfenac and indomethacin demonstrate consistent analgesic efficacy in nearly all patients with panretinal photocoagulation-related pain, while nepafenac 0.3% and diclofenac are effective in a majority of cases. However, heightened panretinal photocoagulation-related pain in females, patients aged ≤ 60 years and those with proliferative diabetic retinopathy may necessitate careful consideration in these populations.